CSO | Sensory Seed
Blaine, MN, UNITED STATES
Dr. TR Hudrlik has been a Biomedical/Biophysics Research Scientist and Inventor for over 35 years.
BSEE, Electrical Engineering
M.S. Biophysics, Biophysics
MSEE, Electrical Engineering
Tucker, R.D., Hudrlik, T.R., Silvis, S.E., and Ackerman, E.
An automated system for measuring biological impedances is described. A microcomputer system is utilized for experimental control, data acquisition, and data reduction. The developed software uses high-level languages and the ability to mix subroutines written in different languages, which are available for microcomputer systems. The software control of analog-to-digital and digital-to-analog conversions is also discussed. The pitfalls, as well as the advantages, of employing a microcomputer system in a task-dedicated laboratory system are presented.view more
Tucker, R.D., Hudrlik, T.R., Gibbs, G.E., and Christensen, M.
The short circuit current rat jejunum bioassay, first employed in an attempt to discern the cystic fibrosis (CF) serum "factor," was evaluated using sera from patients with pancreatic disease. The data suggest other pancreatic diseases, specifically genetic diabetes and alcoholic pancreatitis, also present with a serum "factor" (or "factors") which reduce the short circuit current of rat jejunum, an effect very similar to that of the CF serum "factor." A large number of sera from presumed normal subjects also exhibited a significant reduction in short circuit current; these (false positives) represent a yet to be defined mechanism, however, they do decrease the likelihood that the observed effect is merely due to pancreatic destruction. Detailed procedure and equipment specifications for the bioassay system are included.view more
T.R. Hudrlik, O.H. Schmitt, S.E. Silvis and J.A. Vennes.