Professor of Medical Microbiology
Norwich, UNITED KINGDOM
His work focuses on rapid & more precise detection of antibiotic resistance in order to identify the most appropriate antibiotic treatments.
Ph.D., Medical Microbiology
Eastern Daily Press online
The study’s co-chief investigator, Prof David Livermore from UEA’s Norwich Medical School, said: “We know that some Covid-19 patients get secondary pneumonias but it’s a new disease and no one knows what types of bacteria are most likely.view more
Atlanta Journal Constitution online
"The great majority of strains of ESBL-E. coli causing human infections aren't coming from eating chicken, or anything else in the food chain," lead author David Livermore said in a statement. "The likeliest route of transmission for ESBL-E. coli is directly from human to human, with fecal particles from one person reaching the mouth of another.view more
"Infections caused by ESBL-E. coli bacteria are difficult to treat. And they are becoming more common in both the community and hospitals," David Livermore of the University of East Anglia's Norwich Medical School said. Livermore said mortality rates among people infected with these superbug strains are double those of people infected with strains that are susceptible to treatment.view more
CTV News online
"Infections caused by ESBL-E. coli bacteria are difficult to treat. And they are becoming more common in both the community and hospitals," David Livermore of the University of East Anglia's Norwich Medical School said.view more
Express & Star online
Professor David Livermore, from the University of East Anglia’s Norwich Medical School, who is the study’s main author, said: “The great majority of strains of ESBL-E.coli causing human infections aren’t coming from eating chicken, or anything else in the food chain.view more
Cefiderocol is a parenteral siderophore cephalosporin, with a catechol-containing 3′ substituent. We evaluated its MICs against gram-negative bacteria, using iron-depleted Mueller-Hinton broth. The panel comprised 305 Enterobacterales, 111 P. aeruginosa and 99 A. baumannii, all selected for carbapenem resistance and multi-resistance to other agents.
Ceftaroline and ceftobiprole inhibit most MRSA and MDR pneumococci. Few direct comparisons of their activity have been published, but in several years (2008, 2013, 2017 and 2018) both were tested in parallel in the BSAC Resistance Surveillance Programme, giving paired results. These are reviewed.
Modern medicine is threatened by the global rise of antibiotic resistance, especially among Gram-negative bacteria. Metallo-β-lactamase (MBL) enzymes are a particular concern and are increasingly disseminated worldwide, though particularly in Asia. Many MBL producers have multiple further drug resistances, leaving few obvious treatment options.
Carbapenem resistance in Gram-negative bacteria is a public health concern. Consequently, numerous government and agency reports discuss carbapenem-resistant Enterobacterales (CRE) and carbapenem-resistant organisms (CROs). Unfortunately, these terms are fuzzy.
We present a successful treatment, with tigecycline monotherapy, of acute prostatitis caused by multidrug-resistant Escherichia coli harboring an NDM-1 carbapemenase along with a CMY-2 cephalosporinase and a TEM ESBL.