Floyd D. Gottwald Chair and Professor, Department of Chemical and Life Science Engineering
Engineering West Hall, Room 403A, Richmond, VA, US
Professor Gupton's research is focused on the development of new technologies that will streamline organic synthesis
Richmond Times-Dispatch print
The School of Engineering received about $5 million from the Bill & Melinda Gates Foundation to create a more cost-effective way to manufacture Dolutegravir. It is the third such grant the foundation has awarded the school. The lead investigator, B. Frank Gupton, professor and chair in the VCU Department of Chemical and Life Science Engineering, said the drug is likely to become a first-line therapy for HIV/AIDS.view more
VASEM Report print
Ling noted that one of the applications he is particularly excited about is providing anti-retroviral therapies for Africans with HIV, a project he is exploring with colleagues at Virginia Commonwealth University. “The drugs could be delivered by drone to patients,” he said. The VCU team, led by Frank Gupton, chair of Chemical and Life Science Engineering, has been funded by the NSF, DARPA and the Bill & Melinda Gates foundation to develop flow chemistry methods that can reduce the cost of the ingredients for drugs needed to treat critical diseases like HIV, tuberculosis, and cancer.view more
WVTF / RadioIQ (NPR Affiliate) radio
Frank Gupton used to work for a major pharmaceutical company, so he knows the ins and outs of making drugs. That means he also knows how, often, many drugs that were invented decades ago, could be created for far cheaper today. Gupton says you’d think manufacturer’s would take a look at that, but they don’t.view more
Life Science Leader online
In his “second career,” professor Gupton has given TED talks and received grants totaling nearly $10 million from the Bill & Melinda Gates Foundation. The title of his talk was “Streamlining Pharmaceutical Processes: The ‘Medicines For All Initiative,’ a multidisciplinary project he is leading that seeks cheaper and more efficient ways to manufacture drugs.Gupton noted how the cost structure between a generic and patented drug is quite dramatic.view more
B. Frank Gupton, chair of the Virginia Commonwealth University School of Engineering’s Department of Chemical and Life Science Engineering, is one of the state’s key innovators. He served on McAuliffe’s biosciences technology roundtable last year and recently helped form the Virginia Drug Development Consortium, a collaboration involving VCU, the University of Virginia and Virginia Tech. “We’re trying to take the innovations that are occurring at the different universities in drug discovery [and] move them down the pipeline and increase the intellectual property value of them,” he explains...view more
"We completed the first phase and we've gotten the chemistry to where it's probably the lowest-cost process you could imagine, using really cheap, inexpensive raw materials and streamlining the chemistry for the process," lead researcher B. Frank Gupton said in the study. "We've reported our results to the Gates Foundation and I believe that they were very pleased with our progress." ...view more
University of Richmond, Richmond, VA.
SelectBio Flow Chemistry Congress San Diego, CA.
Virginia Polytechnic Institute and State University Blacksburg, VA.
University of Mainz Mainz, Germany
CPAC Annual Meeting Rome, Italy
National Science Foundation $ 11,500
April 2014 – Feb. 2015
Boehringer Ingelheim Pharmaceuticals, Inc. $ 50,000
June 2013 - Aug. 2014
Clinton Health Access Initiative $ 24,000
May 2013 – Oct. 2014
Clinton Health Access Initiative $ Clinton Health Access Initiative
May 2012 – March 2013
VCU Presidential Research Incentive Program Award $ 40,000
Jan. 2010 - Dec. 2010
Herein, we report a facile and efficient one-step method for the synthesis of highly active, Pd/Fe 3 O 4 nanoparticles supported on graphene nanosheets (Pd/Fe 3 O 4/G) that exhibit excellent catalytic activity for Suzuki and Heck coupling reactions and that can be ...
N-Chelation-directed C–H activation reactions that utilize the Pd (II)/Pd (IV) catalytic cycle have been previously reported. To date, these reactions employ only homogeneous palladium catalysts. The first use of a solid-supported Pd (II) catalyst [Pd (II) nanoparticles ...
An efficient, sustainable, and continuous method for the preparation of graphene supported palladium nanoparticles (Pd/G) has been developed using microwave irradiation as a heating source for the metal deposition process. The Pd/G produced from this method ...
In this paper, we report a simple, versatile, and rapid method for the synthesis of Pd nanoparticle catalysts supported on Fe 3 O 4, Co 3 O 4, and Ni (OH) 2 nanoplates via microwave irradiation. The important advantage of microwave dielectric heating over ...
Palladium nanoparticles supported on single-or multi-walled carbon nanotubes (Pd/SWCNT and Pd/MWCNT) were prepared by a rapid, solventless method that does not require reducing agents or electric current. The method involves a straightforward process using ...